RoseTTAFold3
Baker lab's all-atom model for assemblies with ligands and nucleic acids
RoseTTAFold3 is the Baker lab's entry in the AlphaFold3 class: a trunk-plus-diffusion architecture that predicts proteins, nucleic acids, small molecules and modifications in one model. It reaches AlphaFold3-class accuracy on assemblies while shipping under a BSD license with open weights. Suited to design-loop validation of binders and enzymes.
RoseTTAFold3 is live on FoldForge — paste a sequence and press Fold.
At a glance
- Input
- Sequences and ligands (FASTA, SDF)
- Output
- All-atom assembly (PDB)
- Developed by
- Baker Lab, UW
- Published
- Baker Lab, 2025 · 2025
#all-atom#diffusion#complexes
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