AlphaFold 2 Multimer
AlphaFold 2 specialized for homo- and hetero-oligomeric complexes
The multimer-trained AlphaFold 2 model folds several chains at once into homo- or hetero-oligomers, using paired and unpaired MSAs across chain boundaries. It inherits AlphaFold 2's Evoformer trunk and adds cross-chain relative position encodings for interfaces. Returns full complex models with per-residue pLDDT and inter-chain PAE.
AlphaFold 2 Multimer is live on FoldForge — paste a sequence and press Fold.
At a glance
- Input
- Protein sequences (FASTA)
- Output
- Complex structure (PDB)
- Developed by
- Google DeepMind
- Published
- Evans et al., bioRxiv 2022 · 2022
#complexes#msa#oligomers
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